Sodium 1-(methacryloyloxy)-2,5-dioxopyrrolidine-3-sulfonate - Names and Identifiers
Sodium 1-(methacryloyloxy)-2,5-dioxopyrrolidine-3-sulfonate - Physico-chemical Properties
Sodium 1-(methacryloyloxy)-2,5-dioxopyrrolidine-3-sulfonate - Introduction
Sodium 1-(methacryloyloxy)-2 is a chemically reactive compound containing a methacrylic acid group, a 1-hydroxy-2, 5-dioxopyrroline-3-sulfonate group, and an activated N-hydroxysuccinimide ester group.
The compound is mainly used for covalent attachment and modification of bioactive molecules in biochemical and biomedical research. It can react with amino groups in amino compounds (such as proteins and peptides) to form stable amide linkages. Sodium 1-(methacryloyloxy)-2, can be used as cross-linking reagents, fluorescent labeling reagents, immunocoupling reagents and enzyme coupling reagents in bioanalytical techniques.
The method for preparing Sodium 1-(methacryloyloxy)-2 can be obtained by reacting methacrylic acid (or its anhydride) with sodium 1-hydroxy-2, 5-dioxopyrroline-3-sulfonate, and then reacting with N-Hydroxysuccinimide ester. The preparation process requires care to maintain the neutral and moisture-free conditions of the reaction system.
When using Sodium 1-(methacryloyloxy)-2, you need to pay attention to its safe use. It is a chemical that has an irritating effect on the skin, eyes and mucous membranes, and direct contact should be avoided. During the operation, it is necessary to wear appropriate protective measures, such as laboratory gloves, safety glasses and laboratory coats. In addition, the compound should be kept away from fire sources and strong oxidants, and stored in a dry, cool place.
Last Update:2024-04-09 20:52:54